This research brief shows how the Project Lead The Way® (PLTW) STEM-based curricula raise student achievement in science, technology, engineering and mathematics courses and help get students ready for college and careers. Analyzing data from the 2006 HSTW Assessment, it looks at how PLTW students are more likely to exceed the HSTW course recommendations and are more prepared to pursue postsecondary studies and advances in the workplace.